Oscillatory regulation of Hes1: Discrete stochastic delay modelling and simulation.

Discrete stochastic simulations are a powerful tool for understanding the dynamics of chemical kinetics when there are small-to-moderate numbers of certain molecular species. In this paper we introduce delays into the stochastic simulation algorithm, thus mimicking delays associated with transcripti...

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Bibliographic Details
Main Authors: Manuel Barrio, Kevin Burrage, André Leier, Tianhai Tian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020117