Assessment of the impact of PTGS1, PTGS2 and CYP2C9 polymorphisms on pain, effectiveness and safety of NSAID therapies
Cyclooxygenase 1 and 2 (COX-1, COX-2) are enzymes that catalyze the first reaction in the arachidonic acid pathway. COXs are the therapeutic target for non-steroidal anti-inflammatory drugs. Inhibition of COX enzymatic activity has an analgesic, anti-inflammatory and sometimes antiplatelet effect. S...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Index Copernicus International S.A.
2020-11-01
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Series: | Postępy Higieny i Medycyny Doświadczalnej |
Subjects: | |
Online Access: | http://phmd.pl/gicid/01.3001.0014.5497 |