The Influence of Single, Tandem, and Clustered DNA Damage on the Electronic Properties of the Double Helix: A Theoretical Study

The Influence of Single, Tandem, and Clustered DNA Damage on the Electronic Properties of the Double Helix: A Theoretical Study

Oxidatively generated damage to DNA frequently appears in the human genome as the effect of aerobic metabolism or as the result of exposure to exogenous oxidizing agents, such as ionization radiation. In this paper, the electronic properties of single, tandem, and clustered DNA damage in comparison...

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Bibliographic Details
Main Author: Bolesław T. Karwowski
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
DNA damage
electronic properties
charge transfer
DFT
(5′<i>R</i>)/(5′<i>S</i>)-5′,8-cyclo-2′-deoxyadenosine
8-oxo-7,8-dihydro-2′-deoxyguanosine
Online Access:https://www.mdpi.com/1420-3049/25/14/3126

Internet

https://www.mdpi.com/1420-3049/25/14/3126

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