Multiple Administrations of 64Cu-ATSM as a Novel Therapeutic Option for Glioblastoma: a Translational Study Using Mice with Xenografts

Glioblastoma is the most aggressive malignant brain tumor in humans and is difficult to cure using current treatment options. Hypoxic regions are frequently found in glioblastoma, and increased levels of hypoxia are associated with poor clinical outcomes of glioblastoma patients. Hypoxia plays impor...

Full description

Bibliographic Details
Main Authors: Yukie Yoshii, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Ming-Rong Zhang, Yoko Oe, Hiroaki Kurihara, Yoshitaka Narita, Zhao-Hui Jin, Atsushi B Tsuji, Keiichiro Yoshinaga, Yasuhisa Fujibayashi, Tatsuya Higashi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317303303