Celiac disease in Iran: a systematic review and meta-analysis
Introduction: Celiac disease (CD) is a chronic autoimmune-mediated disorder with both intestinal and systemic manifestations. The aim of this study was to determine the prevalence of celiac disease in Iran. Methods: We conducted a systematic search on Embase, Pub Med, Web of Science, Google Schola...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Electronic Physician
2017-03-01
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Series: | Electronic Physician |
Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407219/ |
Summary: | Introduction: Celiac disease (CD) is a chronic autoimmune-mediated disorder with both intestinal and systemic
manifestations. The aim of this study was to determine the prevalence of celiac disease in Iran.
Methods: We conducted a systematic search on Embase, Pub Med, Web of Science, Google Scholar, MagIran,
Scientific Information database (SID) and Iranmedex from 2003 through to November 2015. The Der-Simonian/
Laird’s (DL), with a 95% confidence interval employed to estimate the overall pooled prevalence. Heterogeneity
was investigated by using subgroup analysis based on sample size and time of study.
Results: Sixty-three studies with 36,833 participants met inclusion criteria for analysis. The overall prevalence of
celiac disease in 63 studies that had used serological tests for the diagnosis was observed as 3% (95% CI: 0.03- 0.03) and the overall prevalence of celiac disease in studies that had used biopsy method for diagnosis was
observed as 2% (95% CI: 0.01- 0.02).
Conclusion: The prevalence of celiac disease in Iran was similar or even higher than world-wide reported |
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ISSN: | 2008-5842 2008-5842 |