Structure and novel functional mechanism of Drosophila SNF in sex-lethal splicing.

Sans-fille (SNF) is the Drosophila homologue of mammalian general splicing factors U1A and U2B'', and it is essential in Drosophila sex determination. We found that, besides its ability to bind U1 snRNA, SNF can also bind polyuridine RNA tracts flanking the male-specific exon of the master...

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Bibliographic Details
Main Authors: Jicheng Hu, Gaofeng Cui, Congmin Li, Cong Liu, Erchang Shang, Luhua Lai, Changwen Jin, Jiwu Wang, Bin Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731243?pdf=render