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02013 am a22001453u 4500 |
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|a Chai, Jun Meng
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|a Manogiri Sadasivam,
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|a Sevakumaran Vigneswari,
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|a Isolation and identification of P(3HB-co-4HB) producing bacteria from various locations in Kuala Terengganu
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|b Penerbit Universiti Kebangsaan Malaysia,
|c 2019-03.
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|z Get fulltext
|u http://journalarticle.ukm.my/12797/1/48_01_28.pdf
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|a Polyhydroxyalkanoates (PHA) is a microbial bioplastic accumulated as a storage material under limited growth conditions in the presence of excess carbon sources. The ever increasing concern towards the depletion of petroleum resources and problems with utilization of a growing number of synthetic plastics, PHAs are being considered as a potential substitute for production of conventional non-degradable plastics. PHAs have been developed as biomaterials with unique properties for many years. Among all types of PHA, copolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] is widely sought after for biomedical application due to the biocompatibility, non-cytotoxicity and non-genotoxicity. Therefore, the aim of this study is to isolate and identify P(3HB-co-4HB) producers from water and soil sources in Kuala Terengganu. Samples of lake and soil were collected during November 2017 and then screened for P(3HB-co-4HB) producer. A total of 18 isolates were obtained, however only 5 isolates were identified as potential PHA producer. Interestingly, 3 isolates were confirmed as copolymer P(3HB-co-4HB) producer through gas chromatography analysis. These 3 isolated identified bacterial strain were Cupriavidus sp. TMT 11 with the highest 4HB molar fraction of 14.1%. The other 2 isolates were Acinetobacter sp. KPD 13 and Cupriavidus sp. PD 16. The properties of the copolymer P(3HB-co-4HB) produced by wide variety of bacteria isolated can be tailored for various biomedical applications.
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|a en
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