Engineering E. coli for the biosynthesis of 3-hydroxy-γ-butyrolactone (3HBL) and 3,4-dihydroxybutyric acid (3,4-DHBA) as value-added chemicals from glucose as a sole carbon source

Engineering E. coli for the biosynthesis of 3-hydroxy-γ-butyrolactone (3HBL) and 3,4-dihydroxybutyric acid (3,4-DHBA) as value-added chemicals from glucose as a sole carbon source

3-hydroxy-γ-butyrolactone (3HBL) is a versatile chiral synthon, deemed a top value-added chemical from biomass by the DOE. We recently reported the first biosynthetic pathway towards 3HBL and its hydrolyzed form, 3,4-dihydroxybutyric acid (3,4-DHBA) in recombinant Escherichia coli using glucose and...

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Bibliographic Details
Main Authors: Tarasova, Yekaterina (Contributor), Martin, Collin H. (Contributor), Dhamankar, Himanshu Hemant (Author), Prather, Kristala L (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Microbiology Graduate Program (Contributor), Prather, Kristala L. Jones (Contributor), Dhamankar, Himanshu (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-03-01T20:39:43Z.
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