A Model for Resource Competition in CRISPR-Mediated Gene Repression

© 2018 IEEE. CRISPR-mediated gene regulation is known for its ability to control multiple targets simultaneously due to its modular nature: the same dCas9 effector can target different genes simply by changing the associated gRNA. However, multiplexing requires the sharing of limited amounts of dCas...

Full description

Bibliographic Details
Main Authors: Chen, Pin-Yi (Author), Qian, Yili (Author), Del Vecchio, Domitilla (Author)
Format: Article
Language:English
Published: IEEE, 2021-11-09T18:55:10Z.
Subjects:
Online Access:Get fulltext