Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA
<jats:p>Faithful inheritance of mitochondrial DNA (mtDNA) is crucial for cellular respiration/oxidative phosphorylation and mitochondrial membrane potential. However, how mtDNA is transmitted to progeny is not fully understood. We utilized hypersuppressive mtDNA, a class of respiratory deficie...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS),
2021-11-12T14:41:10Z.
|
Subjects: | |
Online Access: | Get fulltext |