Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease

Despite recent discoveries in genome-wide association studies (GWAS) of genomic variants associated with Alzheimer's disease (AD), its underlying biological mechanisms are still elusive. The discovery of novel AD-associated genetic variants, particularly in coding regions and from APOE ε4 non-c...

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Bibliographic Details
Main Authors: He, Liang (Author), Loika, Yury (Author), Park, Yongjin (Author), Bennett, David A (Author), Kellis, Manolis (Author), Kulminski, Alexander M (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-07-13T16:49:45Z.
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