Blood Banking in Living Droplets

• Main Authors: Samot, Josh (Author), Moon, Sangjun (Author), Shao, Lei (Author), Zhang, Xiaohui (Author), Xu, Feng (Author), YoungSeok, Song (Author), Hasan, Onur Keles (Author), Matloff, Laura (Author), Markel, Jordan (Author), Demirci, Utkan (Contributor)
• Other Authors: Harvard University- (Contributor)
• Format: Article
• Language: English
• Published: Public Library of Science, 2011-09-02T15:12:58Z.
• Subjects: Article
• Online Access: Get fulltext

Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation.
National Institutes of Health (U.S.) (NIH R21 EB007707)
Wallace H. Coulter Foundation
United States. Army Medical Research and Materiel Command (Acquisition Activity Cooperative Agreement RO1 A1081534)
Center for Integration of Medicine and Innovative Technology
United States. Army Medical Research and Materiel Command (Acquisition Activity Cooperative Agreement R21 AI087107)
United States. Army. Telemedicine & Advanced Technology Research Center