Histone Modifications at Human Enhancers Reflect Global Cell-Type-Specific Gene Expression

Histone Modifications at Human Enhancers Reflect Global Cell-Type-Specific Gene Expression

The human body is composed of diverse cell types with distinct functions. Although it is known that lineage specification depends on cell-specific gene expression, which in turn is driven by promoters, enhancers, insulators and other cis-regulatory DNA sequences for each gene1, 2, 3, the relative ro...

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Main Authors: Heintzman, Nathaniel D. (Author), Hon, Gary C. (Author), Hawkins, R. David (Author), Kheradpour, Pouya (Contributor), Stark, Alexander (Contributor), Harp, Lindsey F. (Author), Ye, Zhen (Author), Lee, Leonard K. (Author), Stuart, Rhona K. (Author), Ching, Christina W. (Author), Ching, Keith A. (Author), Antosiewicz-Bourget, Jessica E. (Author), Liu, Hui (Author), Zhang, Xinmin (Author), Green, Roland D. (Author), Lobanenkov, Victor V. (Author), Stewart, Ron (Author), Thomson, James A. (Author), Crawford, Gregory E. (Author), Kellis, Manolis (Contributor), Ren, Bing (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-09-17T13:12:26Z.
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