Programmable Sequence-Specific Transcriptional Regulation of Mammalian Genome Using Designer TAL Effectors
The ability to direct functional proteins to specific DNA sequences is a long-sought goal in the study and engineering of biological processes. Transcription activator-like effectors (TALEs) from Xanthomonas sp. are site-specific DNA-binding proteins that can be readily designed to target new sequen...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2013-01-31T20:29:39Z.
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| Subjects: | |
| Online Access: | Get fulltext |