Interaction of Streptavidin-Based Peptide-MHC Oligomers (Tetramers) with Cell-Surface T Cell Receptors
he binding of oligomeric peptide-MHC (pMHC) complexes to cell surface TCR can be considered to approximate TCR-pMHC interactions at cell-cell interfaces. In this study, we analyzed the equilibrium binding of streptavidin-based pMHC oligomers (tetramers) and their dissociation kinetics from CD8[super...
Main Authors: | , , , , , |
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Other Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Published: |
American Association of Immunologists,
2013-03-21T15:17:42Z.
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Subjects: | |
Online Access: | Get fulltext |