Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this...

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Main Authors: Jevtov, Irena (Contributor), Glatter, Timo (Author), Schittenhelm, Ralf B. (Author), Rinner, Oliver (Author), Roguska, Katarzyna (Author), Wepf, Alexander (Author), Junger, Martin A. (Author), Kohler, Katja (Author), Choi, Hyungwon (Author), Schmidt, Alexander (Author), Nesvizhskii, Alexey I. (Author), Stocker, Hugo (Author), Hafen, Ernst (Author), Aebersold, Ruedi (Author), Gstaiger, Matthias (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2013-03-26T18:23:38Z.
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