Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorine(e6)

Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorine(e6)

We have previously shown that a conjugate (MA-ce6) between maleylated serum albumin and the photosensitizer chlorin(e6) (ce6) is targeted in vitro to macrophages via class A scavenger receptors. We now report on the ability of this conjugate to localize in macrophage-rich atherosclerotic plaques in...

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Bibliographic Details
Main Authors: Tawakol, Ahmed (Author), Castano, Ana P. (Contributor), Anatelli, Florencia (Author), Bashian, Gregory (Author), Stern, Jeremy (Author), Zahra, Touqir (Author), Gad, Faten (Author), Chirico, Stephanie (Author), Ahmadi, Atosa (Author), Fischman, Alan J. (Author), Muller, James E. (Author), Hamblin, Michael R. (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: SPIE, 2014-06-05T17:29:03Z.
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