Building biomedical materials layer-by-layer

In this materials perspective, the promise of water based layer-by-layer (LbL) assembly as a means of generating drug-releasing surfaces for biomedical applications, from small molecule therapeutics to biologic drugs and nucleic acids, is examined. Specific advantages of the use of LbL assembly vers...

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Bibliographic Details
Main Author: Hammond, Paula T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hammond, Paula T. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-20T14:58:30Z.
Subjects:
Online Access:Get fulltext
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100 1 0 |a Hammond, Paula T  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemical Engineering  |e contributor 
100 1 0 |a Koch Institute for Integrative Cancer Research at MIT  |e contributor 
100 1 0 |a Hammond, Paula T.  |e contributor 
245 0 0 |a Building biomedical materials layer-by-layer 
260 |b Elsevier,   |c 2014-11-20T14:58:30Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/91645 
520 |a In this materials perspective, the promise of water based layer-by-layer (LbL) assembly as a means of generating drug-releasing surfaces for biomedical applications, from small molecule therapeutics to biologic drugs and nucleic acids, is examined. Specific advantages of the use of LbL assembly versus traditional polymeric blend encapsulation are discussed. Examples are provided to present potential new directions. Translational opportunities are discussed to examine the impact and potential for true biomedical translation using rapid assembly methods, and applications are discussed with high need and medical return. 
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