Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2

Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2

Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyzes trimethylation of histone H3 lysine-27 (H3K27me3). Although repressed, PRC2 targets are generally associated with the transc...

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Main Authors: Kanhere, Aditi (Author), Viiri, Keijo (Author), Araújo, Carla C. (Author), Rasaiyaah, Jane (Author), Bouwman, Russell D. (Author), Pereira, C. Filipe (Author), Brookes, Emily (Author), Walker, Kimberly (Author), Bell, George W. (Author), Pombo, Ana (Author), Fisher, Amanda G. (Author), Young, Richard A. (Contributor), Jenner, Richard G. (Author), Whyte, Warren Anthony (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Whyte, Warren A. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-04-02T15:42:57Z.
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