Modulation of the human hair follicle pigmentary unit by corticotrophin-releasing hormone and urocortin peptides

No === Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction of cAMP with up-regulation of pro-opiomelanocortin gene expression and subsequent production of adren...

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Bibliographic Details
Main Authors: Kauser, Sobia, Slominski, A.T., Wei, E.T., Tobin, Desmond J.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3262