The Activation of ATR in Response to Double-Stranded DNA Breaks
<p>The cellular response to the presence of double-stranded DNA breaks (DSBs) is primarily mediated by the ATM protein kinase. A related kinase, ATR, regulates the responses to dysfunctional DNA replication and is also activated, in an ATM-dependent manner, when breaks occur during S-phase....
Internet
https://thesis.library.caltech.edu/5847/2/JSRL-Thesis.pdfRamírez-Lugo, Juan S. (2010) The Activation of ATR in Response to Double-Stranded DNA Breaks. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EG9Z-0H60. https://resolver.caltech.edu/CaltechTHESIS:05262010-155732939 <https://resolver.caltech.edu/CaltechTHESIS:05262010-155732939>