New Insights into the Roles of Human DNA Damage Checkpoint Protein ATR in the Regulation of Nucleotide Excision Repair and DNA Damage-Induced Cell Death

Integrity of the human genome is frequently threatened by endogenous and exogenous DNA damaging reagents that may lead to genome instability and cancer. Cells have evolved multiple mechanisms to repair DNA damage or to eliminate the damaged cells beyond repair and to prevent diverse diseases. Among...

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Bibliographic Details
Main Author: Li, Zhengke
Format: Others
Published: Digital Commons @ East Tennessee State University 2013
Subjects:
ATR
XPA
p53
Bax
Online Access:https://dc.etsu.edu/etd/1782
https://dc.etsu.edu/cgi/viewcontent.cgi?article=2422&context=etd