Low Gene Expression of Excitatory Amino Acid Transporters in Astrocytes of the Locus Coeruleus From Subjects With Major Depressive Disorder

Low Gene Expression of Excitatory Amino Acid Transporters in Astrocytes of the Locus Coeruleus From Subjects With Major Depressive Disorder

Glutamate is a major stress-sensitive excitatory input to the noradrenergic locus coeruleus (LC) and pathology of both glutamatergic and noradrenergic systems is strongly implicated in major depressive disorder (MDD). Glutamatergic innervation of the LC originates in the frontal cortex and in local...

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Bibliographic Details
Main Authors: Szebeni, Katalin, Szebeni, Attila, Chandley, Michelle J., Stockmeier, Craig A., Lutz, E., Ordway, Gregory A.
Published: Digital Commons @ East Tennessee State University 2009
Subjects:
depression
norepinephrine
glia
Biomedical Sciences
Online Access:https://dc.etsu.edu/etsu-works/8629

Internet

https://dc.etsu.edu/etsu-works/8629

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