The Mechanism Of Fragility Of The BCL2 And HOX11 Breakpoint Regions During t(14;18) And t(10;14) Chromosomal Translocations In Lymphoid Cancers
Haematological cancers like leukemia and lymphoma are characterized by genetic abnormalities, specifically chromosomal translocations. Analyses of the translocation breakpoint regions in patients have shown that some loci in the genome are more susceptible to breakage than others. However, very litt...
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| Language: | en_US |
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2014
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| Online Access: | http://etd.iisc.ernet.in/handle/2005/2358 http://etd.ncsi.iisc.ernet.in/abstracts/3032/G24861-Abs.pdf |