Vincristine Metabolism and the Role of CYP3A5
Indiana University-Purdue University Indianapolis (IUPUI) === Vincristine is metabolized by the cytochrome P450 3A subfamily of enzymes possibly including CYP3A5, a genetically polymorphic enzyme. The contribution of CYP3A5 to the metabolism of vincristine was quantified by various in vitro models:...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1805/1168 |