Discovery, Characterization, and Development of Small Molecule Inhibitors of Glycogen Synthase

Discovery, Characterization, and Development of Small Molecule Inhibitors of Glycogen Synthase

Indiana University-Purdue University Indianapolis (IUPUI) === The over-accumulation of glycogen appears as a hallmark in various glycogen storage diseases (GSDs), including Pompe, Cori, Andersen, and Lafora disease. Glycogen synthase (GS) is the rate-limiting enzyme for glycogen synthesis. Recent...

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Bibliographic Details
Main Author: Tang, Buyun
Other Authors: Hurley, Thomas D.
Language:en_US
Published: 2020
Subjects:
Cell model
Enzymology
Glycogen synthase
High-throughput screening
Small molecules
X-ray crystallography
Online Access:http://hdl.handle.net/1805/23200

Internet

http://hdl.handle.net/1805/23200

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