The role of tyrosine phosphorylated caveolin-1 in regulating focal adhesion dynamics and cancer cell migration
Caveolin-1 (Cav1) is a conditional tumor suppressor whose expression is associated with a poor prognosis for many human cancer types. Cavi is a Src kinase substrate phosphorylated on tyrosine-14 (pYl4Cavl) that interacts with integrin and has been localized to focal adhesions (FAs). We undertook to...
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| Language: | English |
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University of British Columbia
2009
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| Online Access: | http://hdl.handle.net/2429/15218 |