Hyaluronan turnover in hyaluronidase 3- and β-hexosaminidase-deficient mice

Hyaluronan (HA) is a glycosaminoglycan that is abundant in the extracellular matrix of vertebrate cells. Under physiological conditions HA exists in a high-molecular-weight form, whereas HA fragments accumulate at sites of tissue injury and inflammation. Hyaluronidases are a group of enzymes that in...

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Bibliographic Details
Main Author: Arja, Vasantha
Other Authors: Triggs-Raine, Barbara (Biochemistry and Medical Genetics)
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1993/3917