Regulation of Toll-like Receptor Signal Transduction Pathways

The stimulation of Toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs) activates macrophages and dendritic cells to response to pathogens. These activated cells induce many immune-related genes, including proinflammatory cytokines which are necessary to activate immune respo...

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Bibliographic Details
Main Author: Lu, Yong-Chen
Other Authors: Ohashi, Pamela S.
Language:en_ca
Published: 2009
Subjects:
TLR
Online Access:http://hdl.handle.net/1807/17796