Antigen-binding Fragments: Production for and Use in Crystallographic Studies
An immunoglobulin (IgG) consists of two antigen-binding fragments (Fab) connected to a crystallisable fragment through hinge regions. This thesis mainly investigates the production methods of Fabs used in structural studies. A cost effective and time saving protocol has been established for the prod...
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Language: | en_ca |
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2013
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Online Access: | http://hdl.handle.net/1807/43090 |