The Imprinting Effects of Mechanical Environment on the Fibrogenesis of Mesenchymal Stem Cells
When routine repair mechanisms fail to regenerate severe burn wounds, mesenchymal stem cell therapy is considered. However, engrafted mesenchymal stem cells are prone to become myofibroblasts when exposed to high mechanical tension and pro-fibrotic cytokines in the wound microenvironment. Myofibrobl...
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| Language: | en_ca |
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2014
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| Online Access: | http://hdl.handle.net/1807/44039 |