Thermodynamics and kinetics of antisense oligonucleotide hybridization to a structured mRNA target

Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, February 2002. === Includes bibliographical references (p. 165-178). === Antisense oligonucleotides have the potential to selectively inhibit the expression of any gene with a known sequence. Antisense-based thera...

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Bibliographic Details
Main Author: Walton, S. Patrick (Stephen Patrick), 1973-
Other Authors: Martin Y. Yarmush and Gregory N. Stephanopoulos.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2008
Subjects:
Online Access:http://hdl.handle.net/1721.1/43615