The Effect of Mutating RUNX1 Binding Site on HIV-1 Replication and Novel HIV-1 Latency Reversal through Using Clinically Prescribed Benzodiazepines
<p> The major barrier to curing HIV-1 infection is latency. HIV-1 latent cells are those in which the viral genome has been integrated into the host cell genome but the virus does not produce the primary infectious agents, viral RNA and proteins. Latency can occur when the virus directly infec...
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Language: | EN |
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University of the Sciences in Philadelphia
2019
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Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=13862426 |