Allosteric interactions at the M3 muscarinic acetylcholine receptor
The extracellular loops of muscarinic acetylcholine receptors are predicted to play a role in the binding and regulation of allosteric modulators. Furthermore, the sequence of the five subtypes of muscarinic receptors shows a large degree of diversity in this region. M3 receptor mutants, K523E, D518...
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Format: | Doctoral Thesis |
Language: | English |
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Universitat Politècnica de Catalunya
2008
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Online Access: | http://hdl.handle.net/10803/6469 http://nbn-resolving.de/urn:isbn:9788469199954 |