Targeted Auger Electron Radiotherapy of HER2-amplified Breast Cancer

Monoclonal antibodies (mAbs) conjugated to nuclear localization sequences (NLS) and labeled with Auger electron-emitters have great potential for targeted radiotherapy of cancer. This approach may be especially appropriate for the 25-30% of patients with breast cancer whose tumors display overexpres...

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Bibliographic Details
Main Author: Costantini, Danny
Other Authors: Reilly, Raymond Matthew
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/17745