FACTORS GOVERNING INTRINSIC CHEMICAL REACTIVITY DIFFERENCES BETWEEN CLAVULANIC AND PENICILLANIC ACID AND ZINC PDB SURVEY: ANALYSES OF ZINC BINDING SITES IN PROTEIN CRYSTAL STRUCTURES

碩士 === 國立清華大學 === 化學系 === 90 === To help elucidate why penicillin-G is inhibited by certain bacterial -lactamase enzymes, whereas clavulanic acid (Clav, which is similar to penicillin-G except at positions 1, 2 and 6) relieves this inhibition, the intrinsic chemical reactivity of these t...

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Bibliographic Details
Main Authors: Yen-lin Lin, 林妍伶
Other Authors: Carmay Lim
Format: Others
Language:zh-TW
Published: 2002
Online Access:http://ndltd.ncl.edu.tw/handle/98939094764005850254