| Summary: | 碩士 === 臺北醫學大學 === 護理學研究所 === 97 === Cancer has been the leading cause of death in Taiwan. The breast cancer has been listed as the 4th cause of cancer death among woman in Taiwan. Besides surgical intervention for breast cancer, the treatment should be included with some kind of adjuvant therapies. The chemotherapy is one of the beneficial remedies. However, during the course of the chemotherapy, the patient not only suffered from the symptoms caused by the therapy but also had decreased physical activities. The aim of this study is to evaluate the association between physical activities and symptom-associated distress in post-operative breast cancer patients receiving chemotherapy and to compare the change of the symptom-associated distress with time and after receiving home-base walking program. An experimental study design was used in this study. The sbjects were randomly assigned into the experimental group and the control group. The instrument used in the study included: demographic data collection form, M. D. Anderson Symptom Inventory-Taiwan Form (MDASI-Taiwan Form), and seven-day physical activity recall (7-day PAR). In addition, individual heart rate monitor was used in exercise group to analyze the subject’s heart rate during exercise. A home-based walking exercise program was designed for the experimental group for 12 weeks (30 minutes a day, three days a week.) Data were collected on the day the patient was scheduled to received the second or third course of chemotherapy (as the first observation date) and on the sixth week and on the twelfth week of the study. The data were analyzed by percentage, mean, standard deviation, Chi-square, t-test, Person’s correlation, one-way ANOVA, two-way ANOVA.
Thirty-two subjects was included this study (14 in the experimental group and 18 in control). The result of the study showed as follwingt: (1) The mean age of the subject was 51.66 ±7.72years. (2) The majority of the patient was with stage II breast cancer and most of the majority of the patients received modified radical mastectomy operation (84.4%); the majority of the patient received chemotherapy of Cyclophoshamide + Epirubicin + 5Fluorouracil (CEF) (64.3%). (3) After 12 weeks of the home-based walking exercise program, experimental group increase physical activity 50.68 METs/week，control group decrease 5.3 METs/week. (4)The symptom-associated distress reached the highest level in the sixth week in control group( p< .01). (5) The physical activity is not relevant to the score from the symptoms( p＞ .05).
The home-based walking exercise is safe and convenient for post- operative breast cancer women. For the purpose to increase physical activity and to avoid increasing symptom distress, breast cancer patients receiving chemotherapy should be able to carry out moderate to heavy walking exercise 30 minutes a day and three days a week.
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