Separation of Positional Mono-PEGylated Teriparatide Isomers Using Reverse-Phased Chromatography Assisted by Solubility Parameter Calculation
碩士 === 國立中央大學 === 化學工程與材料工程學系 === 101 === Teriparatide, a peptide drug for treating to osteoporosis by once-daily injection, is the 1-34 segment of recombinant human parathyroid hormone. However, Teriparatide is proteolytically instable in human serum resulting in short circulation half-life (less t...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2013
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Online Access: | http://ndltd.ncl.edu.tw/handle/49558201281915593103 |