Investigation of properties of multi-phasecalcium sulfate bone substitute

• Main Authors: Yu-ChangLai, 賴佑昌
• Other Authors: Jiin-Huey Chern Lin
• Format: Others
• Language: zh-TW
• Published: 2014
• Online Access: http://ndltd.ncl.edu.tw/handle/y2s226

碩士 === 國立成功大學 === 材料科學及工程學系 === 102 === Calcium sulfate has been used as a substitute for bone defects over decades, with the lower strength and the degradation rate in human body is too fast. In part 1 we try to make calcium sulfate as bonetissue rebuild scaffold due to its low strength and its chemical composition, we make a porous structure with difference porosity, and compared them with in vitro test, and test the properties. In part 2 we try to find out specific ratio between calcium sulfate dihydrate(CSD) particles and calcium sulfate hemihydrate(CSH) powder that can perform good workability and compared them with in vitro test for their properties. In both of them, changing the manufacturing process changes the properties obviously, scaffold with higher porosity has lower strength and dissolve faster. With higher calcium sulfate dehydrate concentration, changes the workability, properties and dissolve lower in SBF Key words: calcium sulfate, porous, bio-degradable, bone cement