Combination of Mesenchymal Stem Cells-delivered Oncolytic Virus and Prodrug Activation Increases Efficacy and Safety in Cancer Therapy

碩士 === 國立陽明大學 === 臨床醫學研究所 === 102 === Oncolytic viruses, such as conditionally replicative adenoviruses (CRAds), have been successfully approved in clinical trials for cancer therapy. However the anti-tumor efficacy was still not ideal. Gene-directed enzyme-prodrug therapy (GDEPT), that is prodrug a...

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Bibliographic Details
Main Authors: Mei-Hsuan Wu, 吳美萱
Other Authors: Shih-Chieh Hung
Format: Others
Language:en_US
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/56722525246889477551