The Mechanism of Camptothecin Derivative to Regulate HIF-1alpha Expression
碩士 === 中臺科技大學 === 醫學檢驗生物技術系碩士班 === 104 === Sirtuin ( SIRT1) is a NAD+- dependent deacetylase protein, and a longevity-associated protein, which regulates hypoxia-inducible factor-1α（HIF-1α）. HIF-1α, a transcription factor, is a key regulator to hypoxia. In the present study, Irinotecan （CPT-11）, cam...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2016
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| Online Access: | http://ndltd.ncl.edu.tw/handle/85664400483203298086 |