| Summary: | 碩士 === 長庚大學 === 醫務管理學系 === 105 === Objective: We compared the effects of 12-week-duration interventions with nutritional, physical exercise, and combination treatment versus control in reducing frailty among community dwelling pre-frail and frail older adults.
Methods: A total of 269 participants who were the outpatients of Miaoli General Hospital, Ministry of Health and Welfare, who agreed to participate were recruited for this study. Participants were randomized into four groups: (1) general care (control), (2) exercise intervention, (3) nutrition intervention, (4) exercise plus nutrition intervention. Frailty score, physical function, nutrition score, and Short Form 12 (SF-12) were assessed at baseline, 4 weeks, and 12 weeks. The generalized estimating equations (GEE) model was used to compare the between-group frailty improvement with adjustment for time and treatment-by-time interactions.
Results: After adjusting for other factors, when compared with control, exercise intervention and combination intervention were shown to improve lower limb muscle strength and the flexibility of the lower back. No significant effects in reducing frailty.
Conclusions: During the intervention period (baseline to 12-week), 40 (40/241; 16.6%) of the pre-frail or frail participants improved to robust. Our findings indicate that 12-week-duration interventions with exercise, and exercise plus nutrition intervention were effective improving muscle strength and flexibility of community dwelling pre-frail and frail older adults.
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