Development of a skew corrugated microfluidic mixer and its application on concentration generator

• Main Authors: Jing-Jie Chen, 陳敬傑
• Other Authors: Yu-Hsiang Hsu
• Format: Others
• Language: zh-TW
• Published: 2017
• Online Access: http://ndltd.ncl.edu.tw/handle/v8h72z

碩士 === 國立臺灣大學 === 應用力學研究所 === 105 === In this paper, we present our study on a new type of passive micromixer based on a skew corrugated configuration. Periodic geometrical barriers like washboard were built inside a microfluidic channel that alters the flow patterns transversely and vertically. The advantages of this type of mixer is its mixing barriers are at the bottom of the microfluidic channel, and it does not need a complex 2-D or 3-D configurations to perform mixing process. This micromixer can easily be fabricated by one step SU-8 photolithographic process and one molding process. Solutions to be squeezed vertically and laterally while encounter the periodic barriers. Thus, the laminar flow pattern is distorted to create mixing process. To study the mixing mechanism of the skew corrugated micromixer, we studied 4 different design parameters to optimize the mixing efficiency. Finite element simulation was conducted to study the mixing pattern and efficiency. This study also proposes a rapid hot embossing process that allows rapid reprinting of thin-film microfluidic device, which can reach 100 microns thickness. The developed technology could enable the feasibility to use the presented micromixer and thin-film plastic chip for commercialization.