Design and Synthesis of Inhibitors Targeting the Hepatitis C Virus NS3 Serine Protease and the Aspartic Protease BACE-1
This thesis describes the synthesis of molecules designed to inhibit the hepatitis C virus (HCV) NS3 serine protease and the human aspartic protease BACE-1, and it also reports the structure-activity relationships between potential inhibitors and the targeted enzymes. In addition, consideration is g...
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| Format: | Doctoral Thesis |
| Language: | English |
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Linköpings universitet, Organisk Kemi
2009
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17850 http://nbn-resolving.de/urn:isbn:978-91-7393-642-2 |