The cell cycle regulators p18Ink4c and p19Ink4d : in vivo studies of their roles in tumorigenesis and development
Progression through the G1, S, G2 and M phases of the cell cycle is controlled by cyclin-dependent kinases (Cdks) and cyclins. These proteins form active Cdk:cyclin complexes that phosphorylate specific substrates. The Cdk:cyclin complexes of the G1/S transition regulate the progression of cells int...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet)
2007
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1357 http://nbn-resolving.de/urn:isbn:978-91-7264-393-2 |