Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis
Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g., infliximab, a chimeric antibody targeting the pro-inflammatory cytokine TNF t...
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| Format: | Doctoral Thesis |
| Language: | English |
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Umeå universitet, Klinisk immunologi
2011
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-42954 http://nbn-resolving.de/urn:isbn:978-91-7459-143-9 |