The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.
The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation. P...
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| Format: | Others |
| Language: | Swedish |
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Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2011
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160700 |