Development of biophysical methods for characterization of PROTACs
Targeting protein with the aim of ubiquitin-labelling for degradation is a new and upand coming field of drug discovery. Proteolysis targeting chimeras (PROTACs) areheterobifunctional linker molecules that connects the target molecule to an E3ubiquitin ligase, subsequent ubiquitination of the target...
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| Format: | Others |
| Language: | English |
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Uppsala universitet, Biokemi
2021
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455225 |