MATHEMATICAL MODELING OF SPECIES-SPECIFIC DIACYLGLYCEROL DYNAMICS IN THE RAW 264.7 MACROPHAGE FOLLOWING P2Y6 RECEPTOR ACTIVATION BY URIDINE 5-DIPHOSPHATE.
In this dissertation, we develop and analyze a mathematical model of the G-protein signaling pathway in RAW 264.7 macrophages downstream P2Y6 activation by the ubiquitous signaling nucleotide uridine 5'-diphosphate. Our model is based on time-course measurements of P2Y6 surface receptors, inosi...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2007
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-06212007-223551/ |