THE ROLE OF HEMOZOIN IN DISEASE: OXIDATIVE STRESS
Infecting 200 million people chronically, Schistosoma mansoni, the helminth responsible for schistosomiasis, catabolizes host hemoglobin releasing amino acids and heme. To avoid the oxidative stress caused by toxic free heme, the heme aggregates into a biomineral known as hemozoin, which is compris...
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| Language: | en |
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VANDERBILT
2009
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-12092009-184929/ |